Searchable abstracts of presentations at key conferences in endocrinology

ea0037ep862 | Thyroid cancer | ECE2015

Anaplastic thyroid carcinoma: The failure of conventional therapy but the real promise of targeted therapy

Lennon Paul , Deady Sandra , Healy Marie-Louise , Kinsella John , Timon Conrad , O'Neill James Paul

Introduction: Anaplastic thyroid cancer is a devastating disease with median survival between 1.2 and 10 months. The disease accounts for as little as 0.9–1.6% of total thyroid cancer cases, but may account for up to half of all thyroid cancer mortality. The aim of our study is to evaluate the prognostic factors and outcomes of patients diagnosed with anaplastic thyroid cancer in Ireland and review emerging treatments for this disease.Methods and de...

ea0037ep883 | Thyroid cancer | ECE2015

Aggressive medullary thyroid cancer in a homogenous population

Lennon Paul , Deedy Sandra , Green Andrew , Kinsella John , Timon Conrad , O'Neill James Paul , Healy Marie-Louise

Introduction: Medullary thyroid cancer arises from the calcitonin-secreting parafollicular C cells and consists of a spectrum of disease that ranges from extremely indolent tumours, where patients may survive for many years with a large tumor burden, to aggressive types associated with a high mortality rate. The objective of our study is to evaluate the prognostic factors and outcomes of patients diagnosed with medullary thyroid cancer in a homogenous population, and to examin...

ea0037ep910 | Thyroid cancer | ECE2015

Thyroid cancer in Ireland: a 10-year review of the National Cancer Registry

Lennon Paul , Deedy Sandra , Healy Marie-Louise , Kinsella John , Timon Conrad , O'Neill James Paul

Introduction: The increased incidence of thyroid cancer is driven mainly by a large increase in papillary thyroid cancer (PTC). The number of patients that succumb to the disease has remained stable. The aim of our study is to analyze the incidence and mortality of thyroid cancer in Ireland.Methods and design: A retrospective analysis of the National Cancer Registry was undertaken, between 1st of January 1998 and the 31st December 2007. The Kaplan–M...